Keywords
diagnosis
symptoms
risk factors
indoor allergens.
How to Cite
Abstract
Asthma is a pediatric disease widely distributed in the world. At the present time there are more than 130 million asthmatics people and the projections in health indicate that this number wrath in increase. In Colombia the morbidity and mortality of asthma are elevated, in spite of this in Santa Marta the asthma prevalence and risk factors is not known. In order to determine what are the environmental and population risk factors associated with the allergic asthma in children of 4 to 16 years from Santa Marta, a trasversal descriptive study was done. The risk factors and asthma severity were determined by means of a standardized questionnaire. The clinical diagnosis of asthma was confirmed by espirometric test. Of a total of 227 children, 97 displayed one or more wheezing or recurrent stridor in the last 12 months, 55 were confirmed by espirometric test. Significant association between asthma symptomatology and house dust exposition, smoking, inheritance and intestinal parasitism was found. None statistical association between asthma and acute or chronic desnutritrion was found. These results confirm the importance of indoor allergens in the asthma symptomatology in the Colombian Caribbean.References
Pearce N, Aït-Khaled N, Beasley R et al. Worldwide trends in the prevalence of asthma symptoms: phase III of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax. 2007; 62(9):758-66.
Neffen H, Baena-Cagnani CE, Malka S. Asthma mortality in Latin America. J Investig Allergol Clin Immunol. 1997; 7(4):249-53.
Taksey J, Craig TJ. Allergy test results of a rural and small-city population compared with those of an urban population. J Am Osteopath Assoc. 2001; 101(5 Suppl):S4-7.
Mallol J, Solé D, Asher I, Clayton T, Stein R, Soto -Quiroz M. Prevalence of asthma symptoms in Latin America: the International Study of Asthma and Allergies in Childhood (ISAAC). Pediatr Pulmonol. 2000 Dec; 30(6):439- 44.
Mallol J. Satellite symposium: Asthma in the World. Asthma among children in Latin America. Allergol Immunopathol (Madr). 2004; 32(3):100-3.
Valenzuela P, Gómez G, Galleguillos F. Prevalencia del asma bronquial en escolares de Santiago, Chile. Rev Méd. Chile 1981; 109: 259-66.
Mallol J, Cortez E, Amarales L et al. The prevalence of asthma in schoolchildren in Montevideo (Uruguay). Allergol Immunopathol (Madr). 1989; 17(1):15-9.
Caraballo L, Cadavid A, Mendoza J. Prevalence of asthma in a tropical city of Colombia. Ann Allergy. 1992; 68(6):525-9.
Robertson CF, Bishop J, Sennhauser FH, Mallol J. International comparison of asthma prevalence in children: Australia, Switzerland, Chile. Pediatr Pulmonol. 1993; 16(4):219-26.
Dennis R, Caraballo L, García E et al. Prevalencia de asma y otras enfermedades alérgicas en Colombia. Rev Coloma Neumol. 1999; 11: 13-23.
Jones MH, Howard J, Davis S, Kisling J, Tepper RS. Sensitivity of spirometric measurements to detect airway obstruction in infants. Am J Respir Crit Care Med. 2003; 167(9):1283-1286.
WHO- World Health Organization. Physical status: the use and interpretation or anthropometry. Technical Report Series. Geneva: World Health Organization. 1995: 6 - 32.
Platts-Mills TAE, De Weck A. Dust mite allergens and asthma- A world wide problem. Bulletin of the World Health Organization, 1989; 66:768 - 780.
Platts-Mills TAE, Thomas WR, Aalberse RC, Vervloet D, Chapman MD. Dust mite allergens and asthma: report of the Second International Workshop. 1992; J Allergy Clin Immunol 89: 1046 - 1060.
Nieto A, Alvarez-Cuesta E, Boquete M, Mazón A, de la Torre F. The cost of asthma treatment in Spain and rationalizing the expense. J Investig Allergol Clin Immunol. 2001; 11(3):139-48.
Stelmach W, Bry³a M, Stelmach I, Maniecka-Bry³a I, Korzeniewska A, Kuna P.. Bronchial asthma epidemiology, public and economic problems. Pol Merkur Lekarski. 2002; 12(72):509-14.
Van Gysel D, Govaere E, Verhamme K, Doli E, De Baets F. The influence of bedroom environment on sensitization and allergic symptoms in schoolchildren. J Investig Allergol Clin Immunol. 2007; 17(4):227-35.
Cole Johnson C, Ownby DR, Havstad SL, Peterson EL. Family history, dust mite exposure in early childhood, and risk for pediatric atopy and asthma. J Allergy Clin Immunol. 2004; 114(1):105-10.
Groneberg-Kloft B, Kraus T, Mark A, Wagner U, Fischer A. Analysing the causes of chronic cough: relation to diesel exhaust, ozone, nitrogen oxides, sulphur oxides and other environmental factors. J Occup Med Toxicol. 2006; 18; 1:6.
Bonay M, Aubier M. Air pollution and allergic airway diseases. Med Sci (Paris). 2007; 23(2):187-92.
Ebtekar M. Air pollution induced asthma and alterations in cytokine patterns. Iran J Allergy Asthma Immunol. 2006; 5(2):47-56.
Huss K, Adkinson NF Jr, Eggleston PA et al. House dust mite and cockroach exposure are strong risk factors for positive allergy skin test responses in the Childhood Asthma Management Program. J Allergy Clin Immunol. 2001; 107(1):48-54.
Lapa e Silva JR, Possebon da Silva MD, Lefort J, Vargaftig BB. Endotoxins, asthma, and allergic immune responses. Toxicology. 2000; 152(1-3):31-5.
Palmer LJ, Celedón JC, Weiss ST, Wang B, Fang Z, Xu X. Ascaris lumbricoides infection is associated with increased risk of childhood asthma and atopy in rural China. Am J Respir Crit Care Med. 2002;
(11):1489-93.
Arruda LK, Santos AB. Immunologic responses to common antigens in helminthic infections and allergic disease. Curr Opin Allergy Clin Immunol. 2005; 5(5):399-402.
Soares MF, Mota I., Macedo MS. Isolation of Ascaris suum components which suppress IgE antibody responses. Int. Arch. Allergy Immunol. 1992; 97(1):37- 43.
Pascual CY, Crespo JF, San Martin S et al. Cross-reactivity between IgEbinding proteins from Anisakis, German cockroach, and chironomids. Allergy. 1997; 52(5):514-20.
Antonio MA, Ribeiro JD, Toro AA, Piedrabuena AE, Morcillo AM. Evaluation of the nutritional status of children and adolescents with asthma. Rev Assoc Med Bras. 2003; 49(4):367-71.