Keywords
Keratins
Immunohistochemistry
Molar third
Keratin - 19
Dental sac
How to Cite
Abstract
In included teeth the remnants of the follicular sac originate from odontogenic cysts such as the dentigerous cyst. This cyst is generated by alteration of the epithelium of the enamel organ after the complete formation of the crown due to the accumulation of liquid between the layers of the adamantine epithelium. Radiographic and histopathological studies are used for the diagnosis of these entities, however, the use of some of the odontogenic immunohistochemistry markers can be a diagnostic aid. The aim of this study was to determine the expression of Cytokeratin 19 protein in biopsies processed during 2018 - 2020 of dentigerous cysts and follicular sacs from the Oral and Maxillofacial Pathology service of the School of Dentistry of the Universidad Nacional de Colombia. A case series study was carried out with 20 blocks with a previous histopathological diagnosis of dentigerous cyst. Hematoxylin and eosin staining was performed and later immunohistochemical labeling with Cytokeratin 19 was performed. The results obtained demonstrate the usefulness of cytokeratin as an immunomarker, particularly for the diagnosis of incipient lesions.References
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