Post-traumatic hypertrophic olivary degeneration associated with Holmes tremor: clinical-imaging correlation
PDF (Español (España))
PDF

Keywords

Hypertrophic olivary degeneration
Midbrain hemorrhage
Inferior olivary nucleus
Holmes tremor
Head trauma
Guillain mollaret triangle

How to Cite

Montero-Cruz, E., Mendoza-Ospina, A. ., Aldana-Bocanegra, J. A., Montaño-Lozada, J. M. ., & Castillo-Támara, E. E. (2022). Post-traumatic hypertrophic olivary degeneration associated with Holmes tremor: clinical-imaging correlation. Duazary, 20(2), 139–144. https://doi.org/10.21676/2389783X.5376

Abstract

Hypertrophic olivary degeneration is a disease secondary to damage to the neuronal circuit of the Guillain Mollaret Triangle, generating symptoms as varied as Holmes tremor. This article describes the case of a 52-year-old man, with a history of head trauma in 2016, without mediate sequelae, who progressively presented tremor, associated 5 years later with headache requiring emergency assistance, where studies were carried out and pharmacological therapy was instituted. Finally, it is concluded that post-traumatic lesions in the Guillain Mollaret Triangle can generate movement disorders secondary to hypertrophic olivary degeneration as sequelae, an entity that is rarely diagnosed.
https://doi.org/10.21676/2389783X.5376
PDF (Español (España))
PDF

References

Font R, Ramos J, Torales O, Moreno S, Bondía J, Martí M. Degeneración olivar hipertrófica: formas de presentación en resonancia magnética. Seram. 2021;1(1): 1-21.

Murdoch S, Shah P, Jampana R. The Guillain–Mollaret triangle in action. Pract Neurol. 2016;16(3):243-246. https://doi.org/10.1136/practneurol-2015-001142

Behzadi F, Fiester PJ, Rao D. Bilateral Hypertrophic Olivary Degeneration Following Brainstem Insult: A Retrospective Review and Examination of Causative Pathology. Neurosci Insights. 2021;16. https://doi.org/10.1177/26331055211007445

Wang H, Wang Y, Wang R, Li Y, Wang P, Li J, et al. Hypertrophic olivary degeneration: A comprehensive review focusing on etiology. Brain Res. 2019; 1718:53-63. https://doi.org/10.1016/j.brainres.2019.04.024

Dogan SN. Hypertrophic Olivary Degeneration and Holmes Tremor: Case Report and Review of the Literature. World Neurosurg. 2020; 137:286-290. https://doi.org/10.1016/j.wneu.2020.02.068

Demaerel R, Demaerel P, van Loon J, Decramer T. Limb ataxia after double hit in the Guillain–Mollaret triangle. Acta Neurol Belg. 2020;120(3):771-773. https://doi.org/10.1007/s13760-020-01313-6

Fleet JL, Calver R, Perera GC, Deng Z. Palato-pharyngo-laryngeal myoclonus with recurrent retrograde feeding tube migration after cerebellar hemorrhagic stroke: A case report and review of hypertrophic olivary degeneration. BMC Neurol. 2020;20(1):1-5. https://doi.org/10.1186/s12883-020-01800-6

Wang YL, Gao Y, He PP, Yin J, Dong R, Li X, et al. A meta-analysis of case studies and clinical characteristics of hypertrophic olivary degeneration secondary to brainstem infarction. J Integr Neurosci. 2020;19(3):507-511. https://doi.org/10.31083/j.jin.2020.03.1238

Lycett M, Cui CK, Dragicevich D, Harris R, Ng K. Hypertrophic olivary degeneration associated with bilateral vocal cord adductor dystonia. BMC Neurology 2023 23:1. 2023;23(1):1-4. https://doi.org/10.1186/s12883-023-03123-8

Bulleid L, Hughes T, Leach P. Mollaret’s triangle: An important neuroanatomical territory for all clinicians. Surgical Neurology International. 2021;12(94): 1-3. https://doi.org/10.25259/SNI_625_2020

Zhou J, Liu Y, Ali Shah SZ. Hypertrophic olivary degeneration following cerebral trauma managed with rehabilitation — A case report. J Pak Med Assoc. 2021;71(4):1252-1254. https://doi.org/10.47391/JPMA.1124

Schaller MA, Steidl E, Shrestha M, Deichmann R, Steinmetz H, Seiler A, et al. Multicenter Prospective Analysis of Hypertrophic Olivary Degeneration Following Infratentorial Stroke (HOD-IS): Evaluation of Disease Epidemiology, Clinical Presentation, and MR-Imaging Aspects. Front Neurol. 2021; 12:1124. https://doi.org/10.3389/fneur.2021.675123

Steidl E, Rauch M, Hattingen E, Breuer S, Rudiger J, Grapengeter M, et al. Qualitative and quantitative detectability of hypertrophic olivary degeneration in T2, FLAIR, PD, and DTI: A prospective MRI study. Front Neurol. 2022;13: 950191. https://doi.org/10.3389/fneur.2022.950191

Onen MR, Moore K, Cikla U, Ucer M, Schmidt B, Field A, et al. Hypertrophic Olivary Degeneration: Neurosurgical Perspective and Literature Review. World Neurosurg. 2018;112: e763-e771. https://doi.org/10.1016/j.wneu.2018.01.150

Elnekiedy A, Naguib N, Hamed W, Mekky J, Mamdouh Hassan HH. MRI and neurological presentation of hypertrophic olivary degeneration. Egyptian Journal of Radiology and Nuclear Medicine. 2016;47(3):1019-1029. https://doi.org/10.1016/j.ejrnm.2016.04.019

Zheng B, Wang J, Huang XQ, Chen Z, Gu GF, Luo XJ. Bilateral Hypertrophic Olivary Degeneration after Pontine Hemorrhage: A Case Report. World J Clin Cases. 2022;10(1):289-295. https://doi.org/10.12998/wjcc.v10.i1.289

De Lima Raeder MT, Reis EP, Campos BM, Zamilute IAG, Junior MCF, Reis F. Transaxonal degenerations of cerebellar connections: the value of anatomical knowledge. Arq Neuropsiquiatr. 2020;78(5):301-306. https://doi.org/10.1590/0004-282x20200021

Radu RA, Ionita LM, Terecoasa EO, Marinescu AN, Tiu C. Hypertrophic olivary degeneration after brainstem haemorrhage – A case report. Romanian Journal of Neurology/ Revista Romana de Neurologie. 2019;18(1):45-50. https://doi.org/10.37897/RJN.2019.1.8

Kakei S, Manto M, Tanaka H, Mitoma H. Pathophysiology of Cerebellar Tremor: The Forward Model-Related Tremor and the Inferior Olive Oscillation-Related Tremor. Front Neurol. 2021; 12:954. https://doi.org/10.3389/fneur.2021.694653

Özdemir M, Turan A, Pelin R, Dilli A. Hypertrophic olivary degeneration: A case report. Indian J Radiol Imaging. 2019; 29:435-437. https://doi.org/10.4103/ijri.IJRI_412_18

Cosentino C, Velez M, Nuñez Y, Palomino H, Quispe D, Flores M, et al. Bilateral Hypertrophic Olivary Degeneration and Holmes Tremor without Palatal Tremor: An Unusual Association. Tremor and Other Hyperkinetic Movements. 2016; 6:400. https://doi.org/10.5334/tohm.302

Ogut E, Armagan K, Tufekci D. The Guillain-Mollaret triangle: a key player in motor coordination and control with implications for neurological disorders. Neurosurgical Review. 2023; 46:181. https://doi.org/10.1007/s10143-023-02086-1

Bhatia KP, Bain P, Bajaj N, Elble RJ, Hallet M, Louis ED, et al. Consensus Statement on the classification of tremors. from the task force on tremor of the International Parkinson and Movement Disorder Society. Movement Disorders. 2018;33(1):75-87. https://doi.org/10.1002/mds.27121

Pyrgelis ES, Agapiou E, Angelopoulou E. Holmes tremor: an updated review. Neurological Sciences. 2022;43(12):6731-6740. https://doi.org/10.1007/s10072-022-06352-w

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Copyright (c) 2023 Universidad del Magdalena

Downloads

Download data is not yet available.