Bacterioterapia preventiva de la obesidad en la comunidad de los indios Pima: evidencias científicas

Silvia Llorens-Folgado, Ana Fernández-Rius


Un desequilibrio en la microbiota intestinal (MI) influye en el desarrollo de la obesidad. Una estrategia para tratar la obesidad implicaría restaurar el equilibrio, manipulando la MI. La efectividad del trasplante fecal (TF) en ciertas patologías, la respalda como una terapia alternativa. La comunidad de indios Pima (PI) son referente en el estudio de la etiología de la diabetes mellitus tipo 2 y obesidad. Se analizó el TF como estrategia preventiva en el desarrollo de obesidad en PI. Para ello, se recogieron evidencias científicas mediante una revisión sistemática cualitativa desde el año 2000 al 2013. Los resultados mostraron un aumento del 112% en el número de publicaciones científicas que asocian la salud a la MI. Un 13% de los estudios relacionan una asociación de la MI con la obesidad. No se encontró ningún estudio de la composición de la MI en los PI. Respecto al TF, se encontró que es el tratamiento menos utilizado para restaurar la microbiota. Se concluyó que, existe un creciente interés científico en el estudio de la MI y se evidenciaron dos brechas de investigación: composición de la MI en los PI y estudios acerca del TF, para determinar su efectividad como terapia preventiva de la obesidad. 

Palabras clave

Obesidad; Trasplante Fecal; Microbiota Intestinal

Texto completo:



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